Head of Department

Jeļizaveta Sokolovska

The faculty and researchers of the Department of Clinical and Personalized Medicine provide science-based academic instruction and are actively engaged in research in the fields of internal medicine, infectious diseases, cardiology and cardiac surgery, urology, and radiology. Members of the department participate in national and international scientific and clinical practice-related collaboration networks involving physicians and researchers.

The main research directions include risk factors for diabetes complications, determinants of health literacy, new strategies in interventional cardiology, familial hypercholesterolemia, antimicrobial resistance, severe infections, hospital epidemiology, and behavioral science related to antibiotic consumption.

Andersone Dainaprofessor
Barona Annijalecturer
Biederer Juergenvisiting professor
Bināns Helmutslecturer
Birka Ilzelecturer
Bistrova Arīnasenior expert
Bondare Līgalecturer
Bukovskis Mārisassociate professor
Buliņa Initalecturer
Dumpis Ugaprofessor
leading researcher
Ērglis Andrejsprofessor
Ērglis Mārtiņšlecturer
Fedulovs Aleksejssenior expert
research assistant
Folkmane Ineseprofessor
leading researcher
Folkmanis Kristofsassociate professor
Freimanis Dāvislecturer
Geldnere Kristīnelecturer
researcher
Gilis Daiņuslecturer
Gorjunova Poļinaresident
lecturer
Griķis Kārlislecturer
Grima Lauraresident
Hasnere Sigitalecturer
Ivanova Sofijasenior expert
Jahimoviča Margaritaacting research assistant (PhD student)
senior expert
Jansone Inesesenior expert
Jēgere Sandaassociate professor
research assistant (Dr.)
Kamzola Gintalecturer
Kozirovskis Viktorsassociate professor
Krams Alvilsprofessor
Kriķe Petralecturer
Kumsārs Indulisassociate professor
Kupics Kasparslecturer
Ķūse Velgalecturer
Laduss Arnislecturer
Laiko-Tīfenberga Baibalecturer
Lapsa Laumaclerk
classroom workload coordinator
Latkovskis Gustavsprofessor
Mintāle Ivetaassociate professor
Muižniece Ievalecturer
Ņesterovičs Georgijslecturer
Ozoliņa Marta Annaresident
laboratory assistant
Pīrāgs Valdisprofessor
Plonis Jurisassociate professor
Puķītis Aldisprofessor
Puzirevska Irēnanurse
Radziņa Maijaleading visiting researcher
Riekstiņa Vijaassociate professor
Romašovs Andrislecturer
Roze Rūdolfslecturer
Roziņa Lieneresident
Rubīns Paulslecturer
Saulīte Anna Janalecturer
Sauša Sintijalecturer
Seļicka Elīnalecturer
senior expert
Skruļa Evitalecturer
Sokolovska Jeļizavetaleading researcher
lecturer
Sorokina Milānalecturer
Stāka Aigaassociate professor
leading researcher
Strazdiņš Uldisassociate professor
Šinkarevs Staņislavsresident
Štrenge Kārlislecturer
Tolmane Ievaassociate professor
Trušinskis Kārlisassociate professor
Vaselāne Diānalecturer
Vasiļvolfa Aigalecturer
Vecmuktāns Dāvislecturer
Vilde Aijalecturer
researcher
Vilunas Ērikssenior laboratory assistant
Vjaters Egilsassociate professor
Voita Ievaresearcher
lecturer
Volosnuhins Edgarslecturer
Zaļizko Poļinaassociate professor
Zariņa Danalecturer

 

 

Clinical Research Center:

Jeļizaveta Sokolovska, Leading Researcher, Associate Professor

Aleksejs Fedulovs, Research Assistant

Irēna Puzirevska, Nurse

Sofija Ivanova, Senior Expert

Clinical Research Center (PI Jeļizaveta Sokolovska) study topics include the investigation of risk factors for diabetes complications, the study of modifiable risk factors for type 2 diabetes and prediabetes, as well as factors influencing health literacy. In the field of type 1 diabetes research, the center participates in the international InterDiane consortium, coordinated by the FinnDiane group from Finland.

In recent years, the Clinical Research Center’s research topics have focused on exploring the relationship between intestinal permeability and diabetic kidney disease, the role of diet and glucose variability in the development of low-grade inflammation and diabetes complications, and various risk factors for diabetic retinopathy.

The group employs a range of research methodologies, including observational and interventional studies, dietary intake data collection and analysis, continuous glucose monitoring, clinical assessment of diabetes complications, biomarker analysis in biological samples, among others.

Zaļizko P,….Sokolovska J. Immune cell infiltration correlates with intestinal permeability, inflammation, and gastrointestinal symptoms in type 1 diabetes..J Diabetes Investig. 2026 Jan 28. doi: 10.1111/jdi.70248.

Bunka L, ..Sokolovska J, Elbere I. Dual-approach analysis of gut microbiome in patients with type 1 diabetes and diabetic kidney disease. I.Ann Med. 2025 Dec;57(1):2531254.

Fedulovs A, Janevica J, Kruzmane L, Sokolovska J. Glucose control and variability assessed by continuous glucose monitoring in patients with type 1 diabetes and diabetic kidney disease. Biomed Rep. 2024 Dec 2;22(2):23

Fedulovs A, Sokolovska J. Progression of Diabetic Kidney Disease and Gastrointestinal Symptoms in Patients with Type I Diabetes..Biomedicines. 2023 Sep 29;11(10):2679.

Ahola AJ, Sokolovska J, Verkauskiene R, Forsblom C. Association between symptoms of depression, diabetes complications and vascular risk factors in four European cohorts of individuals with type 1 diabetes - InterDiane Consortium. Diabetes Res Clin Pract. 2020 Dec;170:108495.

Salna, I., Salna, E., Pahirko, ... & Sokolovska, J. (2021). Achievement of treatment targets predicts progression of vascular complications in type 1 diabetes. Journal of Diabetes and its Complications, 35(12), 108072.

Sokolovska J, Ostrovska K, Pahirko L, Varblane G, Krilatiha K, Cirulnieks A, Folkmane I, Pirags V, Valeinis J, Klavina A, Selavo L. Impact of interval walking training managed through smart mobile devices on albuminuria and leptin/adiponectin ratio in patients with type 2 diabetes..Physiol Rep. 2020 Jul;8(13):e14506. doi: 10.14814/phy2.14506.

2026 – 2028, “Exploring the role of the gut-kidney axis in type 1 diabetes”, funded by the Latvian Council of Science lzp-2025/1-0280. LU – leading partner. Project lead: P. Zaļizko; Work package lead: J. Sokolovska. The role of LU is the development of the study design, recruitment of participants, and processing of data and samples.”


2026-2030 - “A Trial To Evaluate the Efficacy of Continuous Glucose Monitoring as Add-on Therapy in People with Newly Diagnosed Type 2 Diabetes” (ATTENTION-T2D). Leading partner – Medical University of Graz. LU lead: J. Sokolovska. The role of LU as a partner is the implementation of an international study on continuous glucose monitoring in newly diagnosed type 2 diabetes patients.”



2023–2025 – “Physics Informed Machine Learning-Based Prediction and Reversion of Impaired Fasting Glucose Management (PRAESIIDIUM)”, Horizon Europe project, Grant Agreement No. 101095672. Leading partner – Spindox Labs, Italy. The University of Latvia's responsibilities within the project include organizing a data collection study involving individuals with overweight or class I obesity, incorporating dietary and physical activity data, as well as contributing to the development of the study’s digital platform and the participant mobile application.


2024–2025 – National Research Programme “Public Health”, project titled “Assessment and Improvement of Health Literacy among the Latvian Population: Development and Validation of a Population-Oriented Informative Educational Platform for the Study and Monitoring of Lifestyle-Related Risks”, project registration number with the Latvian Council of Science: VPP-VM-Sabiedrības_Veselība-2023/1-0003. Leading partner – Pauls Stradiņš Clinical University Hospital. The University of Latvia’s role in the project includes conducting a population-based study on health literacy through in-person surveys and a

· Liquid nitrogen tank and ultra-low temperature freezer (-86 °C) for the storage of biological samples.

· Medical scales, pulse oximeters, tonometers, measuring tapes, and other equipment for participant examinations.

· Refrigerated medical laboratory bench centrifuge, vortex mixer, and mini-centrifuge for sample processing.

· Automated nucleic acid and protein extraction system, tissue sample homogenizer.

· AEG reader for the detection of advanced glycation end-products in the skin.